Ongoing Research Studies

A research study tests or evaluates treatments, such as new or current medications; behavior treatments; medical equipment; clinical therapies; or procedures or programs, to determine if they are safe and effective.

Why Should I Participate?

If you are looking for a way to stop smoking, participating in a research study may be right for you. People in research studies can receive new treatments before they reach the public. You may also help other smokers by contributing to research that could lead to new treatment options in the future.

Who Conducts Research Studies?

There are countless smoking cessation research studies going on around the world to help determine the best, most effective ways to help people stop smoking and stay quit. A number of the studies being run in the United States are funded by the National Institutes of Health (NIH) and carried out by researchers outside of NIH, usually at universities or medical schools.

Where Can I Learn More About Research Studies?

To learn more about smoking research studies currently recruiting around the world, visit the clinicaltrials.gov database.

Studies Currently Recruiting


Study location: University of California, Irvine

Are you looking to quit smoking, but need help? Apply for the Tweet2Quit program today! You will receive a complementary 8-week supply of nicotine patches & gum, as well as the opportunity to earn up to $60 by completing short surveys. Our program can help motivate you to quit smoking using the power of a peer-based support group, all from the convenience of your phone. This study is open to smokers aged 21 to 59 in the continental United States who plan to quit smoking. You must also have a mobile phone with unlimited texting, use some sort of social media regularly, and be willing to tweet with your quit smoking group daily. For further info please click: http://tweet2quit.merage.uci.edu/

mSMART Smoking Study

Study location: Nationwide

Department of Psychiatry at Duke University is conducting a research study on how you take Chantix® (varenicline) medication to quit smoking. You will receive electronic pill bottles called “MEMS Cap” to use while you take your medication. You will need to have an Android or iOS smartphone. If you have recently started taking or planning to take Chantix® (varenicline) to quit smoking, then make the most of your quit attempt by joining the mSMART Smoking Study.

To learn more about the study or volunteer to participate, please contact:

Dr. Jennifer Stevenson
(919) 684 5403

Internet Stop Smoking Study

Study location: Nationwide

Non-profit research institute is conducting an Internet-based stop smoking study with funding from the U.S. National Cancer Institute. Study participants will be randomly assigned to use either (a) a stop smoking program delivered on desktop PC or (b) a stop smoking program that uses both a smartphone app and related text messages. These online programs will help you build — and guide your use of — an action plan of practical strategies to quit smoking that is right for you.

The program is:

  • Free
  • Easy to use
  • Available anytime
  • Confidential and private

Extended Varenicline Treatment for Cigarette Smoking Among Cancer Patients

Study Location: In-person visits in the Chicago area

Quitting smoking is hard, especially for people who are fighting cancer, but Northwestern University's and University of Pennsylvania's Quit for Health program can help. Quit for Health is now offering a clinical research study funded by the National Cancer Institute that is evaluating a new smoking cessation intervention tailored to cancer patients and survivors.

Eligible smokers will receive seven sessions of smoking cessation counseling and receive varenicline, a U.S. Food and Drug Administration (FDA)-approved smoking cessation medication – all at no charge.​ Participants receive $10 for each completed session and an additional $10 for travel.

If you are over the age of 18, diagnosed with cancer within the last five years, and interested in learning more about the study and our specialized smoking cessation treatment, please call (1-877-236-7487) or email Michael Maloney michael.maloney2@northwestern.edu or Allison Carroll allison.carroll@northwestern.edu.

Quit Smoking with your Phone Study – University of Massachusetts Medical School

Study Location: Nationwide (Smartphone app- iPhone)

Are You Ready To Stop Smoking? Use Your Smartphone, Start Today! Would you like to try a program that can give you on-the-go tools and continuous support, wherever you are, without patches or substitutes? If you are eligible, you will never have to leave your home - not for the program, not for lab tests, not for anything! We will ask you to take 4 short online surveys over the next few months. Plus you have a chance to win $500. This study is sponsored by the National Cancer Institute: R21CA184254

See Me Smoke-Free mobile phone app testing

Study Location: Nationwide (U.S.)

If you decide to take part in this University of Arizona research study, you will use See Me Smoke-Free, a quit smoking app for women, on most days for three months. You will be compensated $50 upon completion of three brief surveys during the study period. Eligible participants are female and use an Android phone.

Enrolling in the study takes 15-30 minutes. Download the app on Google Play and select “yes” when asked if you would like to participate in the study.

For questions about the app or the study, please contact the University of Arizona study coordinator at seemesmokefree@email.arizona.edu or 520-626-4188.

Nicotine Patch Research Study

Study Location: Johns Hopkins University

This research study is being done to learn more about brain changes during active smoking and nicotine withdrawal. We will be studying the brain using noninvasive imaging in both smokers and non-smokers. Participants will complete 2 visits, one of which includes staying on a research unit for 3 nights. Compensation up to $600 will be provided for study completion.

For more information, call 410-502-5433 or visit our website at: http://www.hopkinsmedicine.org/psychiatry/research/volunteers.html#subabuse.


A Mobile App for Tobacco Cessation Medication Adherence

Study Location: iPhone

We are developing a mobile health application (app) to help people take Chantix® to quit smoking. If you qualify, you will test the app for 4 weeks, and complete two surveys.

We are looking for people who are taking Chantix® and have an iPhone. If eligible, you will receive:

  • A free iPhone app to help you take Chantix to quit smoking successfully
  • A $50 Amazon Gift Card in compensation for your participation
  • Assurance that your information will be kept completely confidential

If you’re interested in participating, download the RxCoach app on the App Store: https://itunes.apple.com/us/app/rxcoach/id615913150?mt=8, or search for “RxCoach”.

For more information, visit our website at: www.rxcoachapp.com.

New Treatment for Alcohol and Nicotine Dependence

Study Location: San Diego

We are looking for men and women who are motivated to quit or cut down on their smoking and drinking. You may be eligible to participate in our 18-week research trial. This study involves taking a study drug or placebo and attending weekly 1 hour visits.

Topiramate to Aid Smoking Cessation in Alcohol Dependent Men

Study Location: San Diego VA Hospital

We are looking for MEN in early recovery from alcohol dependence. You may be eligible to participate in our 36-week research trial. This study involves taking a study drug or placebo and weekly visits to the San Diego VA Hospital.

Study of Sexual Function and Smoking

Study Location: University of Geneva, Switzerland

The aim of this study is to better understand the links between smoking and sexual function in men and women, a topic that is not well documented. By participating in this study, you contribute to enhancing scientific knowledge on this topic. The questionnaire will take 15 minutes and can be interesting. This study is being conducted by the research team at Stop-tabac.ch, under the direction of Prof. Jean-François Etter at the University of Geneva.

Study of Electronic Cigarette Users

Study Location: University of Geneva, Switzerland

The aim of this study is to better understand who users of e-cigarettes are and how they use these products. By participating in this study, you contribute to enhancing scientific knowledge on this topic. The questionnaire will take 20 minutes and is being conducted by the research team at Stop-tabac.ch.

Craving to Quit - Yale University Quit Smoking Study

Study Location: Smartphone app (iPhone and Android)

Are You Ready To Stop Smoking? Use Your Smartphone, Start Today! Free Mobile App To Help Stop Your Cravings & End The Addiction. Craving to Quit is a free 21-day program developed at Yale University to help you quit smoking through your smartphone. You will get several reminders a day to check in. It only takes a moment and helps keep you on track. We will ask you to take 4 short online surveys over the next few months. You will be compensated for daily check-ins and online surveys. This study is sponsored by the American Heart Association (HIC: 1301011337).

More For You

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