Join a Research Study

A research study tests or evaluates treatments—such as new or current medications, behavior treatments, medical equipment, clinical therapies, procedures, or programs—to determine if they are safe and effective.

Why Should I Participate?

If you are looking for a way to stop smoking, participating in a research study may be right for you. People in research studies can receive new treatments before they reach the public. You may also help other smokers by contributing to research that could lead to new treatment options in the future.

Who Conducts Research Studies?

There are countless smoking cessation research studies going on around the world to help determine the best, most effective ways to help people stop smoking and stay quit. A number of the studies being run in the United States are funded by the National Institutes of Health (NIH) and carried out by researchers outside of NIH, usually at universities or medical schools.

Where Can I Learn More About Research Studies?

To learn more about smoking research studies currently recruiting around the world, visit the database.

Studies Currently Recruiting

Multimodal Neuroimaging Genetic Biomarkers of Nicotine Addiction Severity

Study Location: Baltimore, MD (Local Recruitment)

Quitting smoking is hard. Let us help you through it. If you are 18-60 years old and ready to quit smoking, we need you for a research study on nicotine dependence at the National Institute on Drug Abuse in Baltimore. The study’s treatment plan is customized to your individual needs and includes free nicotine replacement combined with one-on-one counseling. This is a program that offers a research/treatment combination.

  • Earn up to $1690 for completing the study
  • Receive compensation after each study visit
  • Receive an MRI image of your brain on a t-shirt
  • Evening and weekend study appointments available

We want you to succeed. Call today to see if you qualify at 1-866-START NOW or email at

Helping Pregnant Alaska Native Women Quit Smoking

Study Location: Alaska

The Alaska Native Tribal Health Consortium (ANTHC) and the Vermont Center on Behavior and Health at the University of Vermont (UVM) have a study to help Alaska Native pregnant women stop smoking. 

This study is for:

  1. Alaska Native women,
  2. who are pregnant,
  3. smoke cigarettes,
  4. are 18 years or older,
  5. own a smartphone, and
  6. want to join a study to help them quit smoking.

The study will take place during your pregnancy and for six months after your baby is born.

We will ask you to do breath and saliva tests to test for smoking. You will also fill out surveys. Study staff will give you brief counseling to help you quit smoking.

Women in the study can earn up to $350-$1,620.

Fill out this survey to see if you're eligible.

Contact us for more information:

  • Call/Text: (802) 448-0474
  • Email:

Research Study to Help Nondaily Smokers Quit for Good

Study location: Nationwide

Are you smoking nondaily and want to quit? And are you interested in using support materials to help you quit smoking? 

We have been conducting studies to develop materials to help people who do not smoke every day with quitting smoking. We are now comparing three different approaches to test what support materials work best. We are looking for nondaily smokers, who want to quit smoking, and who want to use support materials to help them through quitting smoking. Our study is a randomized trial, that is, study participants will be assigned at random to different groups, where each group receives different smoking cessation support materials. If you smoke cigarettes on some days (but not every day), you may be eligible to participate in this research study conducted by faculty at the MGH-Harvard Center for Addiction Medicine.

Study participation would entail making an attempt to quit smoking while using the assigned support materials to quit smoking over the course of seven weeks, and completing surveys online. There are no in-person study visits.

We will compensate you for your time (up to $150).

To set up a phone screen interview, or get more details, please contact us at 617-724-3129 or at