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Research Studies

What is a Research Study?

A research study tests or evaluates treatments, such as new or current medications; behavior treatments; medical equipment; clinical therapies; or procedures or programs, to determine if they are safe and effective.

Why Should I Participate?

If you are looking for a way to stop smoking, participating in a research study may be right for you. People in research studies can receive new treatments before they reach the public. You may also help other smokers by contributing to research that could lead to new treatment options in the future.

Who Conducts Research Studies?

There are countless smoking cessation research studies going on around the world to help determine the best, most effective ways to help people stop smoking and stay quit. A number of the studies being run in the United States are funded by the National Institutes of Health (NIH) and carried out by researchers outside of NIH, usually at universities or medical schools.

Where Can I Learn More About Research Studies?

To learn more about smoking research studies currently recruiting around the world, visit the database.

Studies Currently Recruiting

Maastricht University Smoking Study

Study Location: Online:

The purpose of this study is to investigate how smokers respond to different types of images. We ask you to visit the website a total of seven times within a maximum time frame of two weeks. During each visit, you will answer some questions and perform a computerized task. Each visit will take approximately 10 minutes of your time.

If you have any questions after reading the information on the study page, please contact the investigators by sending an email to

Nicotine Patch Research Study

Study Location: Johns Hopkins University

This research study is being done to learn more about brain changes during active smoking and nicotine withdrawal. We will be studying the brain using noninvasive imaging in both smokers and non-smokers. Participants will complete 2 visits, one of which includes staying on a research unit for 3 nights. Compensation up to $600 will be provided for study completion.

For more information, call 410-502-5433 or visit our website at:

motiv8 - Online Quit Smoking Program

Study Location: Online

We are testing an online quit smoking program called motiv8. In motiv8, we provide you with educational resources and a carbon monoxide meter to track your progress online. To help motivate you to quit for good, you will make a monetary deposit of any amount you choose. You will earn this deposit back as you reduce and quit smoking. This small "investment" in quitting may be just the motivation you need to commit to quit!

For more information, visit our website at:

A Mobile App for Tobacco Cessation Medication Adherence

Study Location: iPhone

We are developing a mobile health application (app) to help people take Chantix® to quit smoking. If you qualify, you will test the app for 4 weeks, and complete two surveys.

We are looking for people who are taking Chantix® and have an iPhone. If eligible, you will receive:

  • A free iPhone app to help you take Chantix to quit smoking successfully
  • A $50 Amazon Gift Card in compensation for your participation
  • Assurance that your information will be kept completely confidential

If you’re interested in participating, download the RxCoach app on the App Store:, or search for “RxCoach”.

For more information, visit our website at:

New Treatment for Alcohol and Nicotine Dependence

Study Location: San Diego

We are looking for men and women who are motivated to quit or cut down on their smoking and drinking. You may be eligible to participate in our 18-week research trial. This study involves taking a study drug or placebo and attending weekly 1 hour visits.

Topiramate to Aid Smoking Cessation in Alcohol Dependent Men

Study Location: San Diego VA Hospital

We are looking for MEN in early recovery from alcohol dependence. You may be eligible to participate in our 36-week research trial. This study involves taking a study drug or placebo and weekly visits to the San Diego VA Hospital.

Nicotine Patch Study

Study Location: University of Vermont

The Nicotine Patch Study is conducted by the University of Vermont and sponsored by the National Institutes of Health. The study is designed to answer the following question: If a smoker tries to quit smoking using nicotine patches and then smokes one or more cigarettes, is it better to continue patch use or stop using the patches? In the study, eligible smokers will be assigned by chance to either continue or stop nicotine patch use if they smoke after a quit attempt. We will supply free nicotine patches and free telephone counseling to help smokers quit without smokers needing to leave their homes.

For more Information, call 877-437-6055 Or visit

Study participants may be randomly selected to complete two surveys and earn up to $40.

iQuit Smoking

Study location: University of Michigan

Looking for better ways to quit online? Join the iQuit Smoking Study. Everyone who joins will get a scientifically proven personalized stop smoking plan. You may also receive:

  • Free nicotine patches
  • Free phone support

Earn up to $40. Open to adult smokers in the United States who are planning to quit.

Study of Sexual Function and Smoking

Study Location: University of Geneva, Switzerland

The aim of this study is to better understand the links between smoking and sexual function in men and women, a topic that is not well documented. By participating in this study, you contribute to enhancing scientific knowledge on this topic. The questionnaire will take 15 minutes and can be interesting. This study is being conducted by the research team at, under the direction of Prof. Jean-François Etter at the University of Geneva.

Study of Electronic Cigarette Users

Study Location: University of Geneva, Switzerland

The aim of this study is to better understand who users of e-cigarettes are and how they use these products. By participating in this study, you contribute to enhancing scientific knowledge on this topic. The questionnaire will take 20 minutes and is being conducted by the research team at


Study location: University of California, Irvine

Looking to quit smoking but need help? Apply for Tweet2Quit today to join the study. In addition to receiving free nicotine patches, you will interact with other smokers who are trying to quit at the same time you are through social networking. This mobile peer support group may help motivate you to quit smoking on your quit date and stay quit.

This study is open to smokers ages 18 to 59 in the U.S. who are planning to quit smoking cigarettes, have a mobile phone with unlimited texting, use Facebook, and are open to tweeting or texting a quit smoking group daily.

Craving to Quit - Yale University Quit Smoking Study

Study Location: Smartphone app (iPhone and Android)

Are You Ready To Stop Smoking? Use Your Smartphone, Start Today! Free Mobile App To Help Stop Your Cravings & End The Addiction. Craving to Quit is a free 21-day program developed at Yale University to help you quit smoking through your smartphone. You will get several reminders a day to check in. It only takes a moment and helps keep you on track. We will ask you to take 4 short online surveys over the next few months. You will be compensated for daily check-ins and online surveys. This study is sponsored by the American Heart Association (HIC: 1301011337).